Boronic Acids, Biaryls, Grignards and Organolithiums
Creating higher levels of value in pharmaceuticals, organometallic chemistry is an ideal vehicle to address one of the pharmaceutical industries greatest challenges carbon-carbon and carbon-heteroatom bond formation.
Organometallic chemistry can be tailored to reactivity requirements and a wide range of reactions is known for all structural patterns. In addition organometallic reactions can be carefully controlled (particularly at low temperatures), and they provide an extraordinarily high degree of selectivity allowing very pure end products.
Many of the compounds achievable through the use of organometallic chemistry are simply not available by other routes. In other instances, working with organometallics can reduce the number of synthetic steps required to produce a target molecule. This allows the use of less expensive base materials for the synthesis of high value compounds. In these instances, the key feature of organometallic reactions is the high level of value that they add to the resulting products. Euticals has more than fifteen years of experience in the field of organometallic reactions, and a global infrastructure to deliver a wide range of compounds at very large scale, with world-class quality.
A firm foundation
At Euticals, our organolithium and magnesium compound production is based on our world leading halogen organics expertise, our strengths in catalyst development and our ability to perform subsequent syntheses with these compounds. Our portfolio includes the manufacturing and use of virtually all types of organohalides as precursors for organometallic synthesis. Where applicable, we focus on improving production economics by introducing less expensive chloro-derivatives into the synthetic strategy, but our sound knowledge and technology base for bromo compounds allows us to meet all requirements we are challenged with in the field of industrial organometallic synthesis.
Today, we maintain manufacturing and research facilities for organometallics both in Europe and the United States. For us, it is important to focus on the customers' needs and to find the best synthesis route for them. We operate manufacturing equipment for cryogenic and organometallic reactions at all potential scales, which allows us to grow with our customers' demands and to be the right partner for any challenge. In addition, our flexible research and development program assists our customers at all stages of a project, from initial feasibility studies to commercial production.
Core technologies in our organometallic chemistry portfolio
- Lithium technology
- Boronic acids
- C-C, C-N, C-O Coupling
- Synthesis of Heterocycles from organometallic intermediates